| Round | Grand Prix | Date |
|---|---|---|
| 1 | Qatar Grand Prix | 6 March |
| 2 | Indonesia Grand Prix | 20 March |
| 3 | Argentina Grand Prix | 3 April |
| 4 | Americas Grand Prix | 10 April |
| 5 | Portugal Grand Prix | 24 April |
| 6 | Spanish Grand Prix | 1 May |
| 7 | French Grand Prix | 15 May |
| 8 | Italian Grand Prix | 29 May |
| 9 | Catalunya Grand Prix | 5 June |
| 10 | German Grand Prix | 19 June |
| 11 | Netherlands Grand Prix | 26 June |
| 12 | Finland Grand Prix | 10 July |
| 13 | Great Britain Grand Prix | 7 August |
| 14 | Austria Grand Prix | 21 August |
| 15 | San Marino Grand Prix | 4 September |
| 16 | Aragon Grand Prix | 18 September |
| 17 | Japan Grand Prix | 25 September |
| 18 | Thailand Grand Prix | 2 October |
| 19 | 2022 Australian Motorcycle Grand Prix | 14-16 October |
| 20 | Malaysia Grand Prix | 23 October |
| 21 | Valencia Grand Prix | 6 November |
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